A flame burning within

L Ferrucci, A Ble, S Bandinelli, F Lauretani… - Aging clinical and …, 2004 - Springer
Inflammation is a human being's primary defense against threats to homeostasis that are
encountered every day. Especially in old age, when regulatory mechanisms responsible for
inflammatory responses may be ineffective or damaged, the result can be adverse
pathological conditions, and an increased risk of morbidity and mortality. The inflammation
response is a plastic network composed of redundant signaling among several different
mediators. These mediators have a reciprocal relationship with other biological subsystems …