Evidence for aneuploidy and recombination in the human commensal yeast Candida parapsilosis
RE Fundyga, RJ Kuykendall, W Lee-Yang… - Infection, Genetics and …, 2004 - Elsevier
Isolates of Candida parapsilosis, including representatives of the three major sub-species
groups, were screened for single nucleotide polymorphisms (SNPs) by sequencing five
independent loci totaling 4kb per isolate. Group I isolates were highly conserved and in
some cases, group I alleles were found in group II and III strains. Unique alleles were also
associated with groups II and III, consistent with earlier observations of intergroup
divergence. There was no heterozygosity in any strain, and a FACS analysis demonstrated …
groups, were screened for single nucleotide polymorphisms (SNPs) by sequencing five
independent loci totaling 4kb per isolate. Group I isolates were highly conserved and in
some cases, group I alleles were found in group II and III strains. Unique alleles were also
associated with groups II and III, consistent with earlier observations of intergroup
divergence. There was no heterozygosity in any strain, and a FACS analysis demonstrated …