Secreted lipases of Candida albicans: cloning, characterisation and expression analysis of a new gene family with at least ten members
B Hube, F Stehr, M Bossenz, A Mazur… - Archives of …, 2000 - Springer
Extracellular lipolytic activity enabled the human pathogen Candida albicans to grow on
lipids as the sole source of carbon. Nine new members of a lipase gene family (LIP2–LIP10)
with high similarities to the recently cloned lipase gene LIP1 were cloned and characterised.
The ORFs of all ten lipase genes are between 1281 and 1416 bp long and encode highly
similar proteins with up to 80% identical amino acid sequences. Each deduced lipase
sequence has conserved lipase motifs, four conserved cysteine residues, conserved …
lipids as the sole source of carbon. Nine new members of a lipase gene family (LIP2–LIP10)
with high similarities to the recently cloned lipase gene LIP1 were cloned and characterised.
The ORFs of all ten lipase genes are between 1281 and 1416 bp long and encode highly
similar proteins with up to 80% identical amino acid sequences. Each deduced lipase
sequence has conserved lipase motifs, four conserved cysteine residues, conserved …