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The Emperor of All Maladies: A Biography of Cancer (2010)

by Siddhartha Mukherjee

Other authors: See the other authors section.

MembersReviewsPopularityAverage ratingConversations / Mentions
5,3642022,134 (4.29)1 / 349
History. Medical. Sociology. Nonfiction. HTML:Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is "an extraordinary achievement" (The New Yorker)—a magnificent, profoundly humane "biography" of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence.
Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years.

The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer." The book reads like a literary thriller with cancer as the protagonist.

Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
… (more)
Recently added bytleckie, private library, SarahB5040, JD1021, KLamborn, wwitt003, murphy_5, pipzen, BWBW
  1. 42
    The Secret History of the War on Cancer by Devra Davis (lemontwist)
  2. 21
    Illness as Metaphor & AIDS and Its Metaphors by Susan Sontag (caitlinlizzy)
  3. 10
    And the Band Played On: Politics, People, and the AIDS Epidemic by Randy Shilts (DetailMuse)
    DetailMuse: Both are excellent history-of-medicine narratives.
  4. 00
    Grace and Grit: Spirituality and Healing in the Life and Death of Treya Killam Wilber by Ken Wilber (wester)
    wester: A time-slice of cancer history in a personal story, versus the overview of this same history. Close up and panorama view of the same thing.
  5. 00
    The Philadelphia Chromosome: A Mutant Gene and the Quest to Cure Cancer at the Genetic Level by Jessica Wapner (hailelib)
    hailelib: Expands on Mukherjee's discussion of the development and testing of Gleevec.
  6. 00
    p53: The Gene that Cracked the Cancer Code by Sue Armstrong (rodneyvc)
  7. 00
    Last Night in the OR: A Transplant Surgeon's Odyssey by Bud Shaw (JenniferRobb)
    JenniferRobb: Last Night in the OR discusses early liver transplants; The Emperor of All Maladies details the evolution of cancer treatment
  8. 01
    The Gene: An Intimate History by Siddhartha Mukherjee (jigarpatel)
    jigarpatel: Given the relationship between cancer and genetic pathways, Mukherjee's later The Gene (2016) is insightful for the layperson, recommend this as a precursor to The Emperor of All Maladies.
  9. 02
    The Wisdom of the Body: Discovering the Human Spirit by Sherwin B. Nuland (fountainoverflows)
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 Science!: Emperor of Maladies-- book about cancer6 unread / 6kirahelm, July 2012

» See also 349 mentions

English (198)  Spanish (1)  German (1)  Dutch (1)  Italian (1)  All languages (202)
Showing 1-5 of 198 (next | show all)
After listening to this audiobook, I realized I've been surrounded by cancer my whole life, including terminal cases -- my grandma, then my mom. More recently, one of my best friends had a breast removed. Then I got my own -- a squamous cell carcinoma on my leg. Easily removed, but still...

Cancer is among us.

I was hoping for a happy ending to the story, like a complete cure for all. But, no.

The section on smoking made me cringe, as the struggles with the tobacco industry were heating up in the 60s/70s, just when my foolish young self was smoking with my friends. (Fortunately, I was never addicted and quit young.)

One interesting idea from the author -- the way lung cancer can metastasize through the body, the smoking habit can "metastasize" through a social group, especially if the smoker is very outgoing and sociable. But, on the other hand, quitting smoking can also "metastasize" in a social group if the quitter is very sociable, leaving the loners on the periphery to continue smoking.

Like a lot of WWII veterans, my dad came home from the war with a pack of cigarettes in his pocket. The Army provided them for free. But, so the family story goes, his mother wouldn't let him in the door till he threw away his cigarettes. Good for you, Grandma! He never smoked again in his life.

The information on biology and genetics got a little tedious at times and I let my mind wander from the audiobook on occasion. But the personal stories were very engaging. The children's cancers were heartbreaking. And I found myself rooting so hard for these people and their families. (There but for the grace... so far!)

Recommended! ( )
  casey2962 | Dec 16, 2024 |
The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee covers the vast and myriad history of cancer including much of the development of medicine over the centuries. Mukherjee introduces cancer in terms of both its effects on humans and its resilience. He illuminates the path the myriad of treatments have taken over the years reminding the reader that science and medicine require much determination and a willingness to follow through and change direction as the research points in new directions. The Emperor of All Maladies reminds the reader of the benefits of working across borders and cultures to find answers. The history of cancer is rather dark and even eerie at times but leaves one feeling a grudging respect for its tenacity. Mukherjee explains how it adapts to human beings attempts to eradicate it. As Mukherjee draws direct lines between researchers and research findings from around the world that have brought us to where we are today in the treatment of cancer, he reminds us that cooperation often benefits us all more than isolation does. The Emperor of All Maladies puts cancer under the microscope for anyone whose life has been affected by cancer or might someday be affected by cancer, directly or indirectly. ( )
  TLCooper | Dec 15, 2024 |
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За Ñъжаление, по-нататък в книгата не можах да Ñтигна, защото ме победи Ñтилът на пиÑане на автора. Ðе знам така ли пише човекът, или проÑто е иÑкал да направи книгата по-дебела, но непреÑтанните опиÑателни иÑтории които разказва за вÑичко, което е бегло или дори Ñъмнително Ñвързано Ñ Ñ€Ð°ÐºÐ° доÑта бързо Ñтават Ñупер доÑадни.

ИзвинÑвай човек, наиÑтина иÑкам да прочета как е открита боÑта за боÑдиÑване на ракови клетки за да Ñе виждат под микроÑкоп, но Ñлънчевата утрин в коÑто младиÑÑ‚ учен излÑзал от възрожденÑката Ñи къща, поÑтроена от чичо му по поръчка на виенÑки търговец през 15 в. наиÑтина не влиза в плановете ми, още по-малко иÑториÑта на живота на ÑамиÑÑ‚ чичо, еле пък на виенÑÐºÐ¸Ñ Ñ‚ÑŠÑ€Ð³Ð¾Ð²ÐµÑ†, жена му и детето им Ñ ÐºÑ€Ð¸Ð²Ð¾Ð³Ð»ÐµÐ´Ñтво и ишиаÑ.

Книгата има потенциала да бъде много интереÑна, но...
  Longanlon | Nov 19, 2024 |
It was OK, but I probably should have listened to the abridged version. I had hoped it would transcend its subject matter, and it does for brief moments. But the author obviously wanted to stick to what he knows, which is oncology. That's an admirable impulse, really, but in this case it didn't make for the most compelling read. ( )
  spoko | Oct 24, 2024 |

Libro en detalle, mucho detalle, de la historia del tratamiento del cancer.

Si te interesa el tema, te va a encantar. ( )
  trusmis | Aug 12, 2024 |
Showing 1-5 of 198 (next | show all)
It's time to welcome a new star in the constellation of great doctor-writers. With this fat, enthralling, juicy, scholarly, wonderfully written history of cancer, Siddhartha Mukherjee - a cancer physician and researcher at Columbia University - vaults into that exalted company ...
 

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Author nameRoleType of authorWork?Status
Siddhartha Mukherjeeprimary authorall editionscalculated
Hoye, StephenNarratorsecondary authorsome editionsconfirmed

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Epigraph
Illness is the night-side of life, a more onerous citizenship. Everyone who is born holds dual citizenship, in the kingdom of the well and the kingdom of the sick. Although we all prefer to use only the good passport, sooner or later each of us is obliged, at least for a spell, to identify ourselves as citizens of that other place. —Susan Sontag
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To Robert Sandler (1945-1948), and to those who came before and after him.
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Prologue
Diseases desperate grown
By desperate appliance are relieved
Or not at all.

—William Shakespeare,
Hamlet

Cancer begins and ends with people. In the midst of
scientific abstraction, it is sometimes possible to forget
this one basic fact. . . . Doctors treat diseases, but they also
treat people, and this precondition of their professional
existence sometimes pulls them in two directions at once.

—June Goodfield

On the morning of May 19, 2004, Carla Reed, a thirty-year-old kindergarten teacher from Ipswich, Massachusetts, a mother of three young children, woke up in bed with a headache.
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In a damp fourteen-by-twenty-foot laboratory in Boston on a December morning in 1947, a man named Sidney Farber waited impatiently for the arrival of a parcel from New York.
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Quotations
In solving a problem of this sort, the grand thing is to be able to reason backwards. That is a very useful accomplishment, and a very easy one, but people do not practice it much. —Sherlock Holmes, in Sir Arthur Conan Doyle's A Study in Scarlet
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Physicians of the utmost fame Were called at once; but when they came They answered, as they took their Fees, "There is no Cure for this Disease." —Hilaire Belloc
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Its palliation is a daily task, its cure a fervent hope. —William Castle, describing leukemia in 1950
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Civilization did not cause cancer, but by extending human life spans - civilization unveiled it.
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History. Medical. Sociology. Nonfiction. HTML:Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is "an extraordinary achievement" (The New Yorker)—a magnificent, profoundly humane "biography" of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence.
Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years.

The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer." The book reads like a literary thriller with cancer as the protagonist.

Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

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