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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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State-of-the-Art and Novel Approaches in Molecular and Translational Medicine in Europe

edited by

Vasileios Tzounakas

submission deadline 15 Jan 2025 | 7 articles | Viewed by 15862 | Submission Open

Keywords: translational medicine; biomarkers; high throughput techniques; bioinformatics; in vitro and in vivo models; novel therapies; research applications in pathophysiological backgrounds; molecular/biochemical disease characterization

(This special issue belongs to the Section Molecular and Translational Medicine)

The Role of NK Cells in Health and Diseases

edited by Matthew Blunt

submission deadline 15 Jan 2025 | 4 articles | Viewed by 5652 | Submission Open

Keywords: NK cells; lymphoma; multiple myeloma; CLL; AML; leukaemia; immunotherapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Updates on Adrenal Tumors

edited by

Piotr Glinicki

and

Alicja Szatko

submission deadline 15 Jan 2025 | 3 articles | Viewed by 4777 | Submission Open

Keywords: adrenal; neuroendocrine tumor; biomarkers; pheochromocytoma; urinary steroid profile; plasma steroid profile; chromogranin A; granin family protein

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Angiogenesis, Inflammation, and Oxidative Stress in Inflammatory Bowel Diseases

edited by

Mihail Virgil Boldeanu

and Dan Ionuț Gheonea

submission deadline 15 Jan 2025 | 2 articles | Viewed by 2519 | Submission Open

Keywords: inflammatory bowel disease; angiogenesis; inflammation; oxidative stress

(This special issue belongs to the Section Molecular and Translational Medicine)

Lipids and Lipid Metabolism in Cardiovascular Health and Disease

edited by Fei Luo

submission deadline 15 Jan 2025 | 1 articles | Viewed by 885 | Submission Open

Keywords: lipids; lipoproteins; lipid metabolism; cardiovascular health and disease; atherosclerotic cardiovascular disease; lipid-lowering therapy; triglyceride-lowering therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms and Novel Therapeutic Approaches for Arterial and Venous Embolization

edited by Edward W. Lee and Zachary Haber

submission deadline 15 Jan 2025 | Viewed by 378 | Submission Open

Keywords: vascular embolization; new embolic material; tumoral embolization

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Mechanisms and Therapeutic Approaches for Oral Disorders

edited by

Vincenzo Ronsivalle

Marco Cicciu

and Simona Santonocito

submission deadline 20 Jan 2025 | 1 articles | Viewed by 1300 | Submission Open

Keywords: oral diseases; drugs; local drug delivery; periodontitis; causal periodontal therapy; oral potential malignant disorders; oral cancer; oral medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Approaches in Drug Design: The Pathway from Molecular Mechanisms to New Therapeutic Interventions

edited by

Cristina Manuela Dragoi

Alina Crenguța Nicolae

and

Ion-Bogdan Dumitrescu

submission deadline 20 Jan 2025 | 1 articles | Viewed by 1064 | Submission Open

Keywords: drug design; drug development; therapeutic strategies; preclinical and clinical drug research; disease prognosis and response to therapy; drug _target discovery; individualized therapy; pharmacogenomics; novel therapeutics; medicinal chemistry; biologics; personalized medicine; precision medicine

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Cardiomyopathies and Heart Failure: Charting the Future

edited by Ali Amr

submission deadline 31 Jan 2025 | 7 articles | Viewed by 14383 | Submission Open

Keywords: cardiomyopathies; heart failure; risk stratification; management of cardiomyopathies; cardiac imaging; telemedicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Crohn's Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (2nd Edition)

edited by

Dingpei Long

submission deadline 31 Jan 2025 | 11 articles | Viewed by 14039 | Submission Open

Keywords: inflammatory bowel disease; crohn's disease; ulcerative colitis; chronic inflammation; pathophysiological mechanisms; therapeutic approaches; stem cell transplantation; fecal microbiota transplantation; gut microbiome; _targeted therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Biomaterials for Bone Regeneration

edited by

Kyeong-Hyeon Park

submission deadline 31 Jan 2025 | 10 articles | Viewed by 13321 | Submission Open

Keywords: bone regeneration; bone defect; induced membrane technique; bone transport; biomaterials

(This special issue belongs to the Section Biomedical Engineering and Materials)

Inherited Retinal Diseases: From Pathomolecular Mechanisms to Therapeutic Strategies

edited by

José Martín-Nieto

submission deadline 31 Jan 2025 | 4 articles | Viewed by 12897 | Submission Open

Keywords: blindness; gene and protein function; pathogenesis; personalized diagnosis; precision therapy; retina; retinal degeneration.

(This special issue belongs to the Section Molecular and Translational Medicine)

Vascular Malformation: From Pathophysiology, Clinical Manifestations to Novel Therapeutic Approaches

edited by

Hua Su

and Li Ma

submission deadline 31 Jan 2025 | 7 articles | Viewed by 12593 | Submission Open

Keywords: arteriovenous malformation; vascular malformation; hereditary hemorrhagic telangiectasia; KRAS; activin receptor-lime kinase 1; endoglin; angiogenesis; anti-angiogenesis; animal models

(This special issue belongs to the Section Gene and Cell Therapy)

Diagnostic Biomarkers and Novel Therapeutics _targets for Fragile X Syndrome, Autism Spectrum Disorders and Genetic Neurodevelopmental Diseases: Advances and Challenges

edited by Yolanda De Diego-Otero and Rocio Calvo-Medina

submission deadline 31 Jan 2025 | 8 articles | Viewed by 11699 | Submission Open

(This special issue belongs to the Section Molecular and Translational Medicine)

Exploring Acute Coronary Syndrome: Insights from Basic and Clinical Research

edited by

Cristiana Bustea

submission deadline 31 Jan 2025 | 6 articles | Viewed by 11157 | Submission Open

Keywords: acute coronary syndrome; cardiovascular morbidity; myocardial infarction; pathophysiology; diagnostic modalities; therapeutic interventions; translational research

(This special issue belongs to the Section Molecular and Translational Medicine)

SARS-CoV-2 Infection: Focus on Pathophysiological Characteristics, Complications and Effects of Vaccinations

edited by

Barbara Brogna

Marina Piscopo

and

Carlo Brogna

submission deadline 31 Jan 2025 | 1 articles | Viewed by 11081 | Submission Open

Keywords: SARS-CoV-2 complications; SARS-CoV2 prognostic and predictive biomarkers; long COVID-19 and autoimmune disease; COVID-19 and microbiome; artificial intelligence

(This special issue belongs to the Section Microbiology in Human Health and Disease)

New Molecular Insights into the Pathogenesis and Drug Development of Neurodegenerative Diseases

edited by Aifang Cheng and Beika Zhu

submission deadline 31 Jan 2025 | 5 articles | Viewed by 9285 | Submission Open

Keywords: neurodegenerative diseases; pathogenesis; molecular mechanisms; high-throughput drug screening; drug repurposing; cellular and animal models; brain organoids; mode of action; pharmacological evaluations; preclinical study

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Cerebral Hemorrhages: From Pathophysiologic Mechanisms to Therapeutic Strategies

edited by Yingfeng Wan

submission deadline 31 Jan 2025 | 6 articles | Viewed by 9210 | Submission Open

Keywords: hemorrhagic stroke; white matter injury; brain blood barrier; phagocytosis; hemolysis; immune cells; aging; sex difference; vasospasm; blood‒cerebrospinal fluid barrier

(This special issue belongs to the Section Molecular and Translational Medicine)

Personalized Treatment in Cancer Research

edited by

Sarah Allegra

and

Silvia De Francia

submission deadline 31 Jan 2025 | 4 articles | Viewed by 7823 | Submission Open

Keywords: cancer; personalized medicine; personalized treatment; pharmacogenetics; pharmacokinetics; chemotherapy; adjuvant treatment; therapeutic drug monitoring

(This special issue belongs to the Section Cancer Biology and Oncology)

Disease Biomarkers in the Precision Medicine Era: A Comprehensive Multi-Omics Analysis

edited by

Chia-Jung Li

submission deadline 31 Jan 2025 | 4 articles | Viewed by 6314 | Submission Open

Keywords: personalized medicine; disease biomarkers: screening and diagnosis; multi-omics analysis; epidemiology

(This special issue belongs to the Section Molecular and Translational Medicine)

The Role of Telomere and Telomerase in Human Disease

edited by

Orit Uziel

submission deadline 31 Jan 2025 | 4 articles | Viewed by 6195 | Submission Open

Keywords: telomere; telomerase; cancer; aging

(This special issue belongs to the Section Endocrinology and Metabolism Research)

State-of-the-Art Surfactant in Biomedical Application: A Commemorative Issue in Honor of Prof. Tetsuro Fujiwara

edited by

Fumihiko Namba

submission deadline 31 Jan 2025 | 4 articles | Viewed by 6170 | Submission Open

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Integrative Genomic Analysis, Big Data Processing and Programming, and Pharmaco-Informatics in Biomedicine

edited by

Bashir Lawal

submission deadline 31 Jan 2025 | 3 articles | Viewed by 6166 | Submission Open

Keywords: computational genomics; big data processing and programming; cancer genetics; immunobiology; immune checkpoint response prediction; drug _target identification and validation; network pharmacology; pharmacogenomics; system biology; protein– ligand interaction

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Cellular and Molecular Mechanisms in Gastrointestinal Tract Disease

edited by Felipe Leite De Oliveira

submission deadline 31 Jan 2025 | 4 articles | Viewed by 6130 | Submission Open

Keywords: cellular mechanisms; molecular mechanisms; diagnosis; treatment; experimental models; signaling pathways; comorbidities

(This special issue belongs to the Section Cell Biology and Pathology)

Cardiac Arrhythmias and Arrhythmogenic Disorders: Technological Frontiers, Drug Development and Future Directions

edited by Siamak Salavatian

submission deadline 31 Jan 2025 | 4 articles | Viewed by 6122 | Submission Open

Keywords: cardiac arrhythmias; arrhythmias diagnostic; arrhythmias therapy; technological frontiers; personalized medicine; biomarkers; neuromodulation; artificial intelligence

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Mechanism in Inflammation and Immunity

edited by Anella Saviano

submission deadline 31 Jan 2025 | 2 articles | Viewed by 5955 | Submission Open

Keywords: adaptive immunity; autoimmune-based diseases; cyto/chemokines; inflammation; macrophages; natural compounds; nutraceuticals; signaling pathway in arachidonic acid cascade; T-cells; trained immunity

(This special issue belongs to the Section Cell Biology and Pathology)

Sepsis and Septic Shock: From Molecular Mechanism to Novel Therapies

edited by Fuhong Su

submission deadline 31 Jan 2025 | 4 articles | Viewed by 5618 | Submission Open

Keywords: sepsis; septic shock; molecular mechanisms; specific biomarkers; histone

(This special issue belongs to the Section Cell Biology and Pathology)

Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development: 2nd Edition

edited by

Farhad Vahid

submission deadline 31 Jan 2025 | 7 articles | Viewed by 5393 | Submission Open

Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Breast Cancer: New Diagnostic and Therapeutic Approaches

edited by

Erika Bandini

Tania Rossi

and Sara Bravaccini

submission deadline 31 Jan 2025 | 4 articles | Viewed by 4893 | Submission Open

Keywords: breast cancer; breast oncology; circulating tumor cells

(This special issue belongs to the Section Cancer Biology and Oncology)

Neuroinflammation: From Pathophysiologic Mechanisms to Therapeutic Strategies

edited by Li-Ping Zhou

submission deadline 31 Jan 2025 | 3 articles | Viewed by 4848 | Submission Open

Keywords: neuroinflammation; molecular mechanism; anti-inflammation; stem cell-based therapy; cell-free stem-cell-based therapy; immunomodulation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

State-of-the-Art Pain Medicine

edited by

Alaa Abd-Elsayed

submission deadline 31 Jan 2025 | 3 articles | Viewed by 4615 | Submission Open

Keywords: pain medicine; neuromodulation; neurostimulators

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Novel Approaches towards _targeted Head and Neck Cancer Therapies

edited by

Emilia Wiecheć

submission deadline 31 Jan 2025 | 3 articles | Viewed by 4367 | Submission Open

Keywords: EGFR; VEGFR; RET; MET; PI3K; radiotherapy; chemotherapy; immunotherapy; HPV; preclinical HNSCC model; biomarkers of treatment response

(This special issue belongs to the Section Cancer Biology and Oncology)

Angiogenesis and Related Disorders

edited by

Jian Li

submission deadline 31 Jan 2025 | 4 articles | Viewed by 3876 | Submission Open

Keywords: angiogenesis; cardiovascular diseases; cancers; diabetic complications; therapeutic _target; biomarkers; drug development; clinical implementation

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Mechanisms of Antibody-Mediated Rejection and Accommodation in Kidney Transplantation

edited by

Panupong Hansrivijit

and Ayman Al Jurdi

submission deadline 31 Jan 2025 | 2 articles | Viewed by 3771 | Submission Open

Keywords: kidney transplant; transplant immunology; recurrent glomerular disease; clinical trials; rejection; crossmatching; allocation; CMV; BK nephropathy

(This special issue belongs to the Section Molecular and Translational Medicine)

mTOR Signaling in Disease and Therapy

edited by Wenjing Yu and

Chider Chen

submission deadline 31 Jan 2025 | 2 articles | Viewed by 3441 | Submission Open

Keywords: mTOR signaling; tissue engineering; stem cell; disease; therapy; bone; craniofacial; biomedicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Unraveling the Molecular Mechanisms of Heart and Skeletal Muscle Pathologies

edited by

Marie-Louise Bang

and

Edoardo Malfatti

submission deadline 31 Jan 2025 | 2 articles | Viewed by 3393 | Submission Open

Keywords: cardiomyopathies; skeletal myopathies; molecular basis of cardiac and skeletal pathologies; pre-clinical models; including animal and cell-based models.

(This special issue belongs to the Section Cell Biology and Pathology)

The Role of Extracellular Vesicles in Hepatic, Pancreatic and Biliary Diseases

edited by David R. Brigstock and Xinlei Li

submission deadline 31 Jan 2025 | 2 articles | Viewed by 3262 | Submission Open

Keywords: exosome; extracellular vesicle; microvesicle; steatosis; hepatitis; pancreatitis; hepatocarcinoma; pancreatic ductal adenocarcinoma; diabetes; fibrosis; bile duct; liver; pancreas

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms and Novel Therapeutic Approaches for Gliomas

edited by Maria V. Chatziathanasiadou

submission deadline 31 Jan 2025 | 2 articles | Viewed by 2919 | Submission Open

Keywords: glioma; molecular mechanisms; signaling; tumour immunity; tumour metabolism; tumour microenvironment; metabolic therapies; immunotherapies; combination treatment

(This special issue belongs to the Section Cancer Biology and Oncology)

Role of Bone Marrow Niche in Haematological Cancers

edited by

Jehan J. El-Jawhari

submission deadline 31 Jan 2025 | 2 articles | Viewed by 2638 | Submission Open

Keywords: blood cancers; bone marrow; microenvironment; immune stromal interactions; mesenchymal stem cells

(This special issue belongs to the Section Cancer Biology and Oncology)

_targeting the Resistant Tumor Microenvironment in Lymphoma: From Basic Science to Artificial Intelligence

edited by Rada Amin

submission deadline 31 Jan 2025 | 1 articles | Viewed by 2637 | Submission Open

Keywords: lymphoma; tumor microenvironment; tumor– immune cell interaction; immunotherapy; machine learning; bioimaging; artificial intelligence; immunology

(This special issue belongs to the Section Cancer Biology and Oncology)

Genetic and Epigenetics of Kidney Development: Pathologies of Renal Anomalies and Kidney Diseases

edited by Hongbing Liu

submission deadline 31 Jan 2025 | 2 articles | Viewed by 2434 | Submission Open

Keywords: genetics; epigenetics; CAKUT; kidney development; kidney diseases

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advanced Research in Proteinopathies

edited by

Claudia Capitini

and

Manuela Leri

submission deadline 31 Jan 2025 | 1 articles | Viewed by 2370 | Submission Open

Keywords: protein misfolding; oligomers; amyloid fibrils; amorphous aggregates; prion; neurodegeneration; aggregation kinetics; neurotoxicity; drug discovery

(This special issue belongs to the Section Cell Biology and Pathology)

Feature Reviews in Cardiovascular Diseases

edited by

Serafino Fazio

and

Arturo Cesaro

submission deadline 31 Jan 2025 | 3 articles | Viewed by 2289 | Submission Open

Keywords: cardiovascular diseases; heart failure; cardiac arrhythmias; metabolic syndrome; stroke; pulmonary hypertension; peripheral artery disease (PAD); acute coronary syndrome; myocarditis; pericarditis; valvulopathies

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenic RNA Viruses: Mechanisms of Viral Replication, Viral–Host Interactions and Antiviral Development

edited by

Pengfei Ding

submission deadline 31 Jan 2025 | 1 articles | Viewed by 2235 | Submission Open

Keywords: RNA virus; protein– RNA interactions; RNA structure and function; virus– host cell interactions; virus assembly and replication; viral vectors; therapeutic development

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Protein Kinase C Signalling in Health and Disease: A Commemorative Issue in Honor of Prof. Yasutomi Nishizuka

edited by

Aleksandra Romaniuk-Drapała

and

Ewa Totoń

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1916 | Submission Open

Keywords: novel signaling mechanisms; cell metabolism; omnics/signaling; immunity; cancer; neurobiology

(This special issue belongs to the Section Cell Biology and Pathology)

Advanced Research in Diabetic Kidney Disease

edited by

Cristina Gluhovschi

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1916 | Submission Open

Keywords: diabetic kidney disease; chronic kidney disease; end-stage renal disease

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Nano-Medicine: Revolutionizing Therapeutics, Diagnostics, and Regeneration

edited by Sonali Suresh Rohiwal

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1846 | Submission Open

Keywords: drug delivery systems; _targeted therapies; disease detection; tissue regeneration; regenerative medicine; nanomaterials

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Advances in Fabry Disease: From Molecular Insights to Innovative Therapeutics

edited by

Yuri Battaglia

and Concetto Sessa

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1617 | Submission Open

Keywords: fabry disease; lysosomal storage disorder; GLA gene mutations; enzyme replacement therapy; chaperone therapy; physical activity; imagining

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Biomarker Discovery for Cardiovascular Disease

edited by

Qin Fu

and

Haijun Liu

submission deadline 31 Jan 2025 | 2 articles | Viewed by 1520 | Submission Open

Keywords: cardiovascular disease; genomics; transcriptomics; proteomics; metabolomics; multiomics; gene sequencing; liquid chromatography/gas chromatography tandem mass spectrometry; diagnostic biomarkers; biomedicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Coronary Heart Disease: Causes, Pathology and Treatment

edited by

Joseph A. Moutiris

and

Dimitrios A. Vrachatis

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1270 | Submission Open

Keywords: CHD; dyslipidemia; hypertension; diabetes; myocardial infarction; cardiac rehabilitation; cardiovascular prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

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