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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Challenges in Oral Surgery

edited by

Christian Bacci

submission deadline 5 Jan 2025 | 11 articles | Viewed by 23273 | Submission Open

Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Infection, Super Infection and Antimicrobial Management in ICU—2nd Edition

edited by

Luca Brazzi

and

Giorgia Montrucchio

submission deadline 5 Jan 2025 | 3 articles | Viewed by 4497 | Submission Open

Keywords: superinfections; multidrug-resistant pathogens; antimicrobial stewardship; intensive care medicine; bacterial infections and mycoses; viral infections; immunosuppression; disease and emerging infections; arthropod-borne viruses; anti-infective agents; therapeutic drug monitoring

(This special issue belongs to the Section Infectious Diseases)

Current Challenges and Opportunities in Oto-Rhino-Laryngological Surgery

edited by Leonardo Franz,

Gino Marioni

, Cosimo De Filippis and

Elisabetta Zanoletti

submission deadline 10 Jan 2025 | 4 articles | Viewed by 4730 | Submission Open

Keywords: otolaryngology; surgery; otology; skull-base; head and neck; laryngology; rhinology

(This special issue belongs to the Section Otolaryngology)

Atrial Arrhythmias: Diagnosis, Management and Future Opportunities

edited by

Sergio Conti

submission deadline 10 Jan 2025 | 2 articles | Viewed by 3152 | Submission Open

Keywords: atrial fibrillation ablation; atrial tachycardia; atrial flutter; redo; repeat ablation; 3D mapping; mapping technolo-gies and techniques

(This special issue belongs to the Section Cardiology)

Clinical Application of Established and Emerging Biomarkers for Cardiopulmonary Diseases

edited by

Pasquale Ambrosino

and

Mauro Maniscalco

submission deadline 10 Jan 2025 | 3 articles | Viewed by 2968 | Submission Open

Keywords: chronic obstructive pulmonary disease; severe asthma; biomarkers; metabolomics; endothelial function; arterial stiffness; cardiovascular risk

(This special issue belongs to the Section Clinical Laboratory Medicine)

New Insights into Abdominal Surgery

edited by Pietro Fransvea

submission deadline 10 Jan 2025 | 2 articles | Viewed by 1342 | Submission Open

Keywords: acute care surgery; trauma; minimally invasive emergency surgery; artificial intelligence; outcome prediction

(This special issue belongs to the Section General Surgery)

Clinical Therapeutic Advances in Bone Fractures

edited by Simon Hackl and Eva Simone Steinhausen

submission deadline 10 Jan 2025 | Viewed by 316 | Submission Open

Keywords: stem cells; biomechanics; fracture fixation; orthobiologics; rehabilitation; personalized medicine; 3D printing; im-plant coating; nonunion; fracture-related infection

(This special issue belongs to the Section Orthopedics)

Recent Advances and Challenges in Cardiothoracic Surgery

edited by Marco Anile and Vannucci Jacopo

submission deadline 10 Jan 2025 | Viewed by 287 | Submission Open

Keywords: minimally invasive thoracic surgery; RATS; uniportal VATS; lung transplantation; VATS for arrhythmias; new technologies; radiomics; STAS

(This special issue belongs to the Section Cardiology)

Myocardial Infarction with Nonobstructive Coronary Arteries (MINOCA): Current Status, Challenges and Future Directions: 2nd Edition

edited by

Giuseppe Ciliberti

submission deadline 10 Jan 2025 | Viewed by 251 | Submission Open

Keywords: MINOCA; myocardial infarction; acute coronary syndrome; coronary arteries; coronary artery disease; ischemic cardiac disease

(This special issue belongs to the Section Cardiology)

New Insights into Pediatric Otolaryngology

edited by

Artur Niedzielski

and

Grażyna Mielnik-Niedzielska

submission deadline 10 Jan 2025 | Viewed by 192 | Submission Open

Keywords: pediatric otolaryngology; adenoid hypertrophy; otitis media with effusion; hearing loss; central auditory pro-cessing disorders; acute otitis media; rhinosinusitis

(This special issue belongs to the Section Clinical Pediatrics)

Exploring New Horizons: Pathogenic Mechanisms and Therapeutic Frontiers in Ischemic Stroke

edited by Maurizio Acampa

submission deadline 12 Jan 2025 | 3 articles | Viewed by 3205 | Submission Open

Keywords: cardiovascular risk factors; cryptogenic stroke; ESUS; atrial cardiopathy; non-stenosing atherosclerosis; cardioembolism; acute stroke treatment; antiplatelets; anticoagulants

(This special issue belongs to the Section Clinical Neurology)

Current Updates and Advances in Breast Cancer

edited by

Cinzia Solinas

submission deadline 15 Jan 2025 | 24 articles | Viewed by 103630 | Submission Open

Keywords: young; elderly; imaging; early detection; CD4-6K inhibitors; immunotherapy; immune evasion; sacituzumab govitecan; tucatinib; BRCA; survivorship; supportive care

(This special issue belongs to the Section Oncology)

Modern Approaches to Psoriasis: Current Treatments and Future Possibilities

edited by Teresa Battista and

Matteo Megna

submission deadline 15 Jan 2025 | 6 articles | Viewed by 9760 | Submission Open

Keywords: psoriasis; psoriatic arthritis; biologics; small molecules; comorbidities

(This special issue belongs to the Section Dermatology)

Latest Advances in Thoracic Surgery

edited by

Hideki Ujiie

submission deadline 15 Jan 2025 | 4 articles | Viewed by 8006 | Submission Open

Keywords: lung cancer; surgical oncology; robotic surgery; thoracic surgery; lung diseases; minimally invasive surgery

(This special issue belongs to the Section Pulmonology)

Innovations in Neurorehabilitation

edited by

Syoichi Tashiro

submission deadline 15 Jan 2025 | 5 articles | Viewed by 5937 | Submission Open

Keywords: clinical neurophysiology; neuroengineering; robotics; non-invasive transcranial brain stimulation; spinal stimulation; regenerative rehabilitation; neuroimaging; brain– computer interface; brain– spine interface; virtual reality; environmental control systems; higher level cognitive functions; vision rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Ulcers After Bariatric Surgery

edited by Vincenzo Pilone and

Antonio Vitiello

submission deadline 15 Jan 2025 | 4 articles | Viewed by 5118 | Submission Open

Keywords: marginal ulcer; sleeve gastrectomy; Roux-en-Y gastric bypass; one anastomosis gastric bypass; single anastomosis sleeve-ileal bypass; single anastomosis duodeno-ileal bypass; LSG; RYGB; OAGB; SASI; SADI

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Management of Skin Cancer: From Pathology Advances to Techniques Applications

edited by Guy Orchard

submission deadline 15 Jan 2025 | 4 articles | Viewed by 5073 | Submission Open

Keywords: skin cancer; surgery; chemotherapy; radiotherapy; photothermal therapy; combination therapy; molecular _target strategies

(This special issue belongs to the Section Dermatology)

Advances in Burn Management

edited by Juan P. Barret

submission deadline 15 Jan 2025 | 4 articles | Viewed by 5056 | Submission Open

Keywords: burns; wound healing; immune response; stem cells ; burn surgery ; rehabilitation ; PROMs; PREMs

(This special issue belongs to the Section General Surgery)

Challenges in Spinal Deformity

edited by

Peter G. Passias

submission deadline 15 Jan 2025 | 4 articles | Viewed by 3468 | Submission Open

Keywords: osteoarthritis; cartilage; pain; pathogenesis; imaging; epidemiology; randomized controlled trial; cost-effectiveness; platelet rich plasma; stem cells; exercise therapy; arthroplasty; biomaterials

(This special issue belongs to the Section Orthopedics)

Clinical Advances in the Diagnosis and Treatment of Atrial Fibrillation

edited by

Urs Eriksson

submission deadline 15 Jan 2025 | 2 articles | Viewed by 2190 | Submission Open

Keywords: atrial fibrillation; early detection; treatment strategies; personalized treatment approaches

(This special issue belongs to the Section Cardiology)

Clinical Application of Biomarkers in Cancers

edited by

Monica Florescu

submission deadline 15 Jan 2025 | 2 articles | Viewed by 1543 | Submission Open

Keywords: cancer biomarkers; early detection; personalized therapy; biomarker validation; advanced technologies; clinical implementation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Peripheral Nerves: Imaging, Electrophysiology and Surgical Techniques

edited by

Raffaele Natella

, Aniello Iovino and Vito Stifano

submission deadline 15 Jan 2025 | 1 articles | Viewed by 1193 | Submission Open

Keywords: MRI; MSK imaging; soft-tissue tumors; DTI; neuropathies; inflammatory neuropathies; nerve entrapment; motor neuron disease; neurophysiology; MSK ultrasound; peripheral nerve tumor; nerve entrapment; nerve reconstruction

(This special issue belongs to the Section Clinical Neurology)

Hip Surgery: Clinical Treatment and Management: 2nd Edition

edited by

Lukas A. Holzer

submission deadline 15 Jan 2025 | 1 articles | Viewed by 874 | Submission Open

Keywords: total hip replacement; revision total hip replacement; femoroacetabular impingement; hip fracture; hip– spine relationship; developmental dysplasia of the hip

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Headaches: Enhancing Diagnosis, Treatment, and Patient Outcomes

edited by Gary W. Jay

submission deadline 15 Jan 2025 | Viewed by 231 | Submission Open

Keywords: migraine headache; tension-type headache; cluster headache; trigeminal autonomic cephalalgias; hemicrania continua; paroxysmal hemicrania; trigeminal neuralgia

(This special issue belongs to the Section Clinical Neurology)

Advances in Rheumatology: From Bench to Bedside

edited by

Matteo Colina

submission deadline 15 Jan 2025 | Viewed by 228 | Submission Open

Keywords: autoimmune disease; inflammation pathophysiology; novel therapeutic strategies; translational medicine; bench to bedside (B2B); disease biomarkers

(This special issue belongs to the Section Immunology)

Vasculitis in Adults and Children: Symptoms, Diagnosis and Treatment—2nd Edition

edited by

Ryu Watanabe

submission deadline 15 Jan 2025 | Viewed by 224 | Submission Open

Keywords: vasculitis; glucocorticoids; cyclophosphamide; molecularly _targeted therapy; unmet clinical needs; potential therapeutic _targets

(This special issue belongs to the Section Vascular Medicine)

Stress, Rhythms Dysregulation and Bipolar Spectrum

edited by

Mauro Giovanni Carta

and

Giulia Cossu

submission deadline 20 Jan 2025 | 13 articles | Viewed by 15958 | Submission Open

Keywords: bipolar spectrum; neo-Kraepelinian tradition; dimensional approach; social rhythms; chronobiological rhythms

(This special issue belongs to the Section Mental Health)

Advancements in Individualized Plastic and Reconstructive Surgery

edited by

Paul Immanuel Heidekrueger

, Peter Niclas Broer and Denis C. Ehrl

submission deadline 20 Jan 2025 | 10 articles | Viewed by 14278 | Submission Open

Keywords: patient-specific reconstructive procedures; microsurgical precision techniques; autologous tissue transplantation; digital imaging and customization; biomaterials in reconstructive surgery; tissue engineering for plastic reconstruction; flap surgery innovations; personalized cleft surgery; personalized aesthetic surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Epilepsy: Causes, Symptoms, Diagnosis, and Treatment

edited by

Emanuele Bartolini

submission deadline 20 Jan 2025 | 7 articles | Viewed by 14182 | Submission Open

Keywords: neurological diseases; brain; neurology; neuroscience; neuroimaging; fMRI; EEG; genetics

(This special issue belongs to the Section Clinical Neurology)

Total Joint Arthroplasty: Management and Future Opportunities

edited by

Riccardo Giorgino

and

Laura Mangiavini

submission deadline 20 Jan 2025 | 8 articles | Viewed by 10449 | Submission Open

Keywords: total joint arthroplasty; joint replacement; surgical techniques; robotic-assisted surgery; implant materials; post-operative care; patient outcomes; future opportunities; orthopedic surgery; innovation in arthroplasty

(This special issue belongs to the Section Orthopedics)

Clinical Advances and Future Perspectives in Vascular Surgery

edited by

George N. Kouvelos

Konstantinos Spanos

and

Petroula N. Nana

submission deadline 20 Jan 2025 | 7 articles | Viewed by 10343 | Submission Open

Keywords: vascular surgery; endovascular surgery; aortic surgery; peripheral arterial disease; carotid artery disease; EVAR; vascular access; aneurysm; complex aneurysm

(This special issue belongs to the Section General Surgery)

The Current Trend in the Management of Bruxism and Temporomandibular Disorders

edited by

Luís Eduardo Almeida

submission deadline 20 Jan 2025 | 5 articles | Viewed by 9917 | Submission Open

Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Updates on Maternal Fetal Medicine

edited by

Misgav Rottenstreich

and

Roberta Granese

submission deadline 20 Jan 2025 | 6 articles | Viewed by 9529 | Submission Open

Keywords: diabetes in pregnancy; hypertension in pregnancy; cholestasis in pregnancy; endocrine disorder in pregnancy; sepsis in pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Non-small Cell Lung Cancer: Current Updates and Perspectives

edited by

Athina N. Markou

submission deadline 20 Jan 2025 | 3 articles | Viewed by 7650 | Submission Open

Keywords: non-small cell lung cancer (NSCLC); liquid biopsy; cell-free DNA (cfDNA); minimal residual disease (MRD); circulating tumor cells (CTCs); heterogeneity; epithelial– mesenchymal transition (EMT); tyrosine kinase inhibitor (TKI)

(This special issue belongs to the Section Pulmonology)

Clinical Advances in Pulmonary Heart Disease

edited by

Alexandra D. Arvanitaki

and Stephen John Wort

submission deadline 20 Jan 2025 | 3 articles | Viewed by 5437 | Submission Open

Keywords: pulmonary heart disease; pulmonary hypertension; diagnosis; treatment; clinical advances

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Debates in Minimally Invasive Glaucoma Surgery (MIGS)

edited by

Etsuo Chihara

submission deadline 20 Jan 2025 | 4 articles | Viewed by 4069 | Submission Open

Keywords: MIGS (minimally invasive glaucoma surgery); schlemm’ s canal opening surgery; trabeculotomy; trabeculectomy; collector channel; histology; intraocular pressure; surgical success

(This special issue belongs to the Section Ophthalmology)

Guidelines for the Management of Severe Aortic Stenosis

edited by Srikanth Koneru

submission deadline 20 Jan 2025 | 2 articles | Viewed by 3104 | Submission Open

Keywords: aortic stenosis; low flow low gradient AS; TAVR; SAVR; multimodality imaging; valve in valve TAVR; patient prosthesis mismatch

(This special issue belongs to the Section Clinical Guidelines)

The Changing Landscape of Fertility Diagnosis and Treatment

edited by

Amanda N. Kallen

and

David B. Seifer

submission deadline 20 Jan 2025 | 3 articles | Viewed by 2927 | Submission Open

Keywords: infertility; reproductive aging; in vitro fertilization; fertility; ovarian aging; ovary; uterus; sperm; tubal factor infertility; male factor infertility; biomarkers

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Abdominal Hernia Repair: Current Strategies for the Management of Abdominal Wall Hernias

edited by

Sergio Huerta

submission deadline 20 Jan 2025 | 2 articles | Viewed by 2518 | Submission Open

Keywords: inguinal hernia; ventral hernia; femoral hernia; pantaloon hernia; parastomal hernia

(This special issue belongs to the Section General Surgery)

Novel Epidemiological Approaches in Clinical Pharmacology and Toxicology

edited by

Niccolò Lombardi

and

Giada Crescioli

submission deadline 20 Jan 2025 | 2 articles | Viewed by 2453 | Submission Open

Keywords: clinical pharmacology; toxicology; epidemiology; the value of real-world evidence; adverse drug reactions; drug safety

(This special issue belongs to the Section Pharmacology)

Review Special Issue Series: Recent Advances in Pharmacology

edited by

Alfredo Vannacci

and

Giada Crescioli

submission deadline 20 Jan 2025 | 1 articles | Viewed by 1853 | Submission Open

Keywords: clinical pharmacology; pharmacovigilance; pharmacokinetics; pharmacodynamics; pharmacogenetics; pharmacoepidemiology; pharmacometrics; pregnancy and pediatrics; adults and elderly; safety; toxic and side effects; drug reactions

(This special issue belongs to the Section Pharmacology)

Clinical Advances in Cardiac Imaging

edited by

Łukasz A. Małek

submission deadline 20 Jan 2025 | 2 articles | Viewed by 1730 | Submission Open

Keywords: non-invasive imaging; heart; vessels; application; diagnosis; technique

(This special issue belongs to the Section Cardiology)

New Insights into Infectious Skin and Mucosal Diseases

edited by

Giulia Ciccarese

Sebastiano Recalcati

and Astrid Herzum

submission deadline 20 Jan 2025 | 1 articles | Viewed by 1118 | Submission Open

Keywords: exanthem; latent viruses; infectious diseases; skin eruptions; sexually transmitted infections

(This special issue belongs to the Section Dermatology)

New Advances in Cardiovascular Diseases: The Cutting Edge

edited by

Fabiana Lucà

submission deadline 20 Jan 2025 | 1 articles | Viewed by 964 | Submission Open

Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias

(This special issue belongs to the Section Cardiovascular Medicine)

Workplace Bullying and Health Outcomes

edited by

Giuseppe La Torre

and

Gabriele D’Ettorre

submission deadline 20 Jan 2025 | Viewed by 327 | Submission Open

Keywords: epidemiology; public health; occupational medicine; workplace bullying; mental health; patient outcomes; economic assessment

(This special issue belongs to the Section Epidemiology & Public Health)

Advances in the Surgical Management of Gynecological Malignancies

edited by Laurentiu Pirtea and Răzvan Ştefan Ilina

submission deadline 20 Jan 2025 | Viewed by 167 | Submission Open

Keywords: minimally invasive surgery; laparoscopy surgery; robotic-assisted surgery; gynecological malignancies

(This special issue belongs to the Section Obstetrics & Gynecology)

Type 2 Diabetes: Advances and Challenges

edited by Ken-ichi Aihara

submission deadline 22 Jan 2025 | 1 articles | Viewed by 918 | Submission Open

Keywords: type 2 diabetes; clinical research; innovative treatment; biomarker; diabetic complications; glucose monitoring

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Management of Liver Cancers

edited by Jayant Kumar and

Isabella Reccia

submission deadline 23 Jan 2025 | 2 articles | Viewed by 3640 | Submission Open

Keywords: hepatocellular carcinoma; cholangiocarcinoma; mixed hepatocellular carcinoma– cholangiocarcinoma; combined hepatocellular carcinoma-cholangiocarcinoma; liver cancers

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Management of Pelvic Organ Prolapse

edited by

Barbara Bodner-Adler

submission deadline 23 Jan 2025 | 1 articles | Viewed by 1437 | Submission Open

Keywords: pelvic organ prolapse; pessary treatment; uterus-preserving prolapse surgery; clinical management; clinical treatment

(This special issue belongs to the Section Obstetrics & Gynecology)

New Insights into Kidney Transplantation

edited by Sami Alasfar

submission deadline 23 Jan 2025 | 1 articles | Viewed by 911 | Submission Open

Keywords: rejection; organ optimization; transplantation; immunosuppressants; biomarkers; AI; innovation

(This special issue belongs to the Section Nephrology & Urology)

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