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This malaria vaccine is delivered by a mosquito bite

Bites from insects infected with modified malaria parasites boosted immunity and stopped people from contracting the disease.
  1. Helena Kudiabor
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Scientists have developed a new vaccination strategy for malaria — boosting immunity through bites from mosquitoes carrying a genetically engineered version of the parasite that causes malaria. In a trial, the approach reduced participants’ susceptibility to malaria, potentially paving the way for more effective ways to stop the disease, which infects some 250 million people a year.

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doi: https://doi.org/10.1038/d41586-024-03817-0

Updates & Corrections

  • Update 26 November 2024: The image for this story has been updated to show a mosquito that transmits malaria.

References

  1. Lamers, O. A. C. et al. N. Engl. J. Med. 391, 1913–1923 (2024).

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  2. Roestenber, M. et al. Sci. Transl. Med. 12, eaaz5629( 2020).

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