Evaluation of trabectome in open-angle glaucoma
- PMID: 23429629
- DOI: 10.1097/IJG.0b013e3182311b92
Evaluation of trabectome in open-angle glaucoma
Abstract
Purpose: To evaluate the outcomes of Trabectome, a surgical device that ablates an arc of trabecular meshwork, in Japanese glaucoma patients.
Patients and methods: Trabectome surgeries were performed on 80 eyes of 69 adult Japanese patients (age range, 14 to 89 y; 50 male and 30 female patients) with or without previous surgery or laser treatment. Goldmann applanation intraocular pressure (IOP), adjunctive medications, corneal endothelial cell density, and best corrected visual acuity were measured before and after surgery. Intraoperative and postoperative adverse events were also tabulated.
Results: Mean preoperative IOP of 26.6 ± 8.1 mm Hg (range, 16 to 50 mm Hg) decreased to a mean postoperative IOP of 17.4±3.4 mm Hg (range, 9 to 24 mm Hg) (28.7% reduction) by 6 months after surgery (N=53). Adjunctive medication decreased from 4.0 ± 1.4 to 2.3 ± 1.2 at 6 months after surgery. Intraoperative blood reflux occurred in 100% of cases. No vision-threatening complications such as choroidal effusion, choroidal hemorrhage, or infection occurred. Thirteen cases (16.3%) received surgical reintervention and 1 case received cataract extraction during follow-up. No significant endothelial cell density change was recognized.
Conclusion: Trabectome is an effective and safe alternative to traditional glaucoma surgeries with the expectation of approximately a 30% decrease in IOP through 6 months postoperatively.
Similar articles
-
Clinical results with the Trabectome for treatment of open-angle glaucoma.Ophthalmology. 2005 Jun;112(6):962-7. doi: 10.1016/j.ophtha.2004.12.043. Ophthalmology. 2005. PMID: 15882909 Clinical Trial.
-
Ab interno trabeculectomy: outcomes in exfoliation versus primary open-angle glaucoma.J Cataract Refract Surg. 2012 Feb;38(2):315-23. doi: 10.1016/j.jcrs.2011.08.043. J Cataract Refract Surg. 2012. PMID: 22322166
-
Effect of a failed trabectome on subsequent trabeculectomy.J Glaucoma. 2012 Feb;21(2):71-5. doi: 10.1097/IJG.0b013e31820bcfda. J Glaucoma. 2012. PMID: 21336149
-
Review and meta-analysis of ab-interno trabeculectomy outcomes.Br J Ophthalmol. 2016 May;100(5):594-600. doi: 10.1136/bjophthalmol-2015-307131. Epub 2016 Jan 5. Br J Ophthalmol. 2016. PMID: 26733487 Review.
-
[Minimally invasive glaucoma surgery using the trabectome].Klin Monbl Augenheilkd. 2015 Mar;232(3):303-9. doi: 10.1055/s-0034-1383014. Epub 2014 Oct 1. Klin Monbl Augenheilkd. 2015. PMID: 25272086 Review. German.
Cited by
-
Twelve-Month Outcomes of Stand-Alone Excisional Goniotomy in Mild to Severe Glaucoma.Clin Ophthalmol. 2020 Jul 3;14:1891-1897. doi: 10.2147/OPTH.S256423. eCollection 2020. Clin Ophthalmol. 2020. PMID: 32694910 Free PMC article.
-
Results of Trabectome Surgery Following Failed Glaucoma Tube Shunt Implantation: Cohort Study.Medicine (Baltimore). 2015 Jul;94(30):e1045. doi: 10.1097/MD.0000000000001045. Medicine (Baltimore). 2015. PMID: 26222842 Free PMC article.
-
Microinvasive Glaucoma Surgery: An Evidence-Based Assessment.Expert Rev Ophthalmol. 2017;12(4):331-343. doi: 10.1080/17469899.2017.1335597. Epub 2017 Jun 12. Expert Rev Ophthalmol. 2017. PMID: 30026790 Free PMC article.
-
Corneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK).J Ophthalmol. 2022 Jan 30;2022:1315299. doi: 10.1155/2022/1315299. eCollection 2022. J Ophthalmol. 2022. PMID: 35637682 Free PMC article. Review.
-
Safety and Efficacy of Microinvasive Glaucoma Surgery.J Ophthalmol. 2017;2017:3182935. doi: 10.1155/2017/3182935. Epub 2017 Apr 23. J Ophthalmol. 2017. PMID: 28512578 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
