Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016:2016:3410469.
doi: 10.1155/2016/3410469. Epub 2016 Feb 16.

Comparison of Surgical Outcomes between Canaloplasty and Schlemm's Canal Scaffold at 24 Months' Follow-Up

Stefano A Gandolfi  1 , Nicola Ungaro  1 , Stella Ghirardini  1 , Maria Grazia Tardini  1 , Paolo Mora  1
Affiliations

Comparison of Surgical Outcomes between Canaloplasty and Schlemm's Canal Scaffold at 24 Months' Follow-Up

Stefano A Gandolfi et al. J Ophthalmol. 2016.

Abstract

The results of canaloplasty (CP) and Hydrus Microstent (HM) implantation were retrospectively compared at 24 months' follow-up in a cohort of subjects referred to our Institution for uncontrolled IOP in primary or secondary (e.g., pseudoexfoliative and pigmentary) open-angle glaucoma. The outcome was labelled as "complete" success, "qualified" success, or "failure" if, two years after surgery, the eyes operated on needed "no" hypotensive medications, "some" hypotensive medications, or further glaucoma surgery to attain the _target IOP, respectively. Both CP and HM implant allowed significant IOP reductions, with comparable rate of clinical success and safety profile. A slightly (albeit not significant) better trend for a "complete" clinical success was observed in the CP group.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Scatterplot of preoperative (IOP initial) versus postoperative (IOP final) IOP values in the two treatment groups (CP = canaloplasty group; HM = Hydrus Microstent group).
Figure 2
Figure 2
Distribution of eyes (eyes) referred to the number of required hypotensive medications (hypotensive drugs) in each treatment group, preoperatively and at the end of the 2-year follow-up. CP pre: preoperative distribution of eyes addressed to canaloplasty; CP post: distribution of eyes addressed to canaloplasty 24 months after surgery; HM pre: preoperative distribution of eyes addressed to Hydrus Microstent; HM post: distribution of eyes addressed to Hydrus Microstent 24 months after surgery.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Lewis R. A., von Wolff K., Tetz M., et al. Canaloplasty: circumferential viscodilation and tensioning of Schlemm canal using a flexible microcatheter for the treatment of open-angle glaucoma in adults: two-year interim clinical study results. Journal of Cataract and Refractive Surgery. 2009;35(5):814–824. doi: 10.1016/j.jcrs.2009.01.010. - DOI - PubMed
    1. Saheb H., Ahmed I. I. K. Micro-invasive glaucoma surgery: current perspectives and future directions. Current Opinion in Ophthalmology. 2012;23(2):96–104. doi: 10.1097/icu.0b013e32834ff1e7. - DOI - PubMed
    1. Ko G.-Y., Song H.-Y., Seo T.-S., Kim T.-H., Sung K.-B., Yoon H.-K. Obstruction of the lacrimal system: treatment with a covered, retrievable, expandable nitinol stent versus a lacrimal polyurethane stent. Radiology. 2003;227(1):270–276. doi: 10.1148/radiol.2271011674. - DOI - PubMed
    1. Hays C. L., Gulati V., Fan S., Samuelson T. W., Ahmed I. I. K., Toris C. B. Improvement in outflow facility by two novel microinvasive glaucoma surgery implants. Investigative Ophthalmology and Visual Science. 2014;55(3):1893–1900. doi: 10.1167/iovs.13-13353. - DOI - PMC - PubMed
    1. Johnstone M. A., Saheb H., Ahmed I. I. K., Samuelson T. W., Schieber A. T., Toris C. B. Effects of a Schlemm canal scaffold on collector channel ostia in human anterior segments. Experimental Eye Research. 2014;119:70–76. doi: 10.1016/j.exer.2013.12.011. - DOI - PubMed

LinkOut - more resources

  NODES
INTERN 1
twitter 2