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Comparative Study
. 2020 Jul;64(4):407-413.
doi: 10.1007/s10384-020-00750-3. Epub 2020 Jun 12.

Comparison of the short-term effectiveness and safety profile of ab interno combined trabeculotomy using 2 types of trabecular hooks

Takashi Omoto  1   2 , Takashi Fujishiro  3 , Kimiko Asano-Shimizu  1 , Koichiro Sugimoto  1 , Rei Sakata  1 , Hiroshi Murata  1 , Ryo Asaoka  1 , Megumi Honjo  1 , Makoto Aihara  1
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Comparative Study

Comparison of the short-term effectiveness and safety profile of ab interno combined trabeculotomy using 2 types of trabecular hooks

Takashi Omoto et al. Jpn J Ophthalmol. 2020 Jul.

Abstract

Purpose: To compare the short-term surgical effectiveness and safety profile of ab interno trabeculotomy using 2 types of trabecular hooks.

Study design: Retrospective comparative study.

Patients and methods: A retrospective chart review was performed on Japanese open-angle glaucoma patients who underwent ab interno trabeculotomy with phacoemulsification and who had a 6-month follow-up. Trabeculotomy was performed using 2 kinds of trabecular hooks, the Tanito ab interno Trabeculotomy Micro-hook (TMH) or the Kahook Dual Blade (KDB). The patients' demographics, preoperative and postoperative intraocular pressures (IOPs), medication scores, and occurrence of complications were analyzed and compared.

Results: Fifty-nine eyes with open-angle glaucoma were included in the final analysis. Trabeculotomy was performed using the TMH in 30 eyes (50.8%) and the KDB in 29 eyes (49.2%). Significant decreases in IOP from the baseline (P < 0.001, except for the 1-month time-point in the KDB group, when P < 0.01) after the 1-month time-point and the medication scores (P < 0.001) at all time-points were noted in both groups. However, the percentage changes in the IOP and medication scores from the baseline at each time-point did not differ significantly between the 2 groups, with the exception of the medication score at the 1-month time-point (P < 0.0283). The occurrence of postoperative complications was similar in the 2 groups.

Conclusions: The present study demonstrates the absence of significant differences in IOP and medication score reductions at almost all time-points between the TMH and KDB groups.

Keywords: Glaucoma; Intraocular pressure; MIGS; Trabeculectomy; Trabeculotomy.

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