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Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
Cannabis Use During Pregnancy and Neuropsychiatric Adverse Outcomes in Children and Young Adults
Clinical and Practical Psychopharmacology

January 6, 2025

Current research suggests that prenatal cannabis exposure is linked to many adverse outcomes, including psychosis proneness, psychotic-like experiences, internalizing and externalizing problems, attention problems, thought-related problems, social problems, impaired…
JCP
IV Hydroxyzine vs Haloperidol for Delirium
Original Research

January 6, 2025

Hydroxyzine showed a significantly higher rate of delirium improvement than haloperidol, with no significant difference in the time to improvement.
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JCP
Olanzapine/Samidorphan Effects on Weight Gain
Original Research

January 2, 2025

Treatment with a combination of olanzapine and samidorphan was associated with less weight gain and reduced risk of reaching ≥7% or ≥10% gain in body weight versus olanzapine over…
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Vol 85 • 2024 • Number 4

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Meta-Analysis

Changes in Cognition in Patients With Schizophrenia

Systematic Review

Diagnostic Assessment via Telehealth vs Face-to-Face

Original Research

Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans

Original Research

Bridge Symptoms Between Borderline Personality and PTSD

Original Research

Gepirone-ER and Sexual Function in Patients with MDD

Original Research

Medication Use and Lines of Treatment in Patients With Insomnia Disorder
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Focus on Psychosis Focus on Geriatric Psychiatry Focus on Women’s Mental Health Focus on Suicide Early Career Psychiatrists Focus on Psychotherapy

Original Research

JCP
Substance and Opioid Use Disorders Among IBD Hospitalizations
Original Research

January 2, 2025

A higher prevalence of SUD and opioid use disorder was found among hospitalizations for inflammatory bowel disease, and these elevated prevalences were linked to distinct demographic, socioeconomic, and geographic…
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JCP
Treatments and Treatment Predictors in Patients With SUDs and ADHD
Original Research

December 23, 2024

Treatment site explained more of the variation in ADHD treatment provision than patient factors. Higher ADHD symptom severity and sobriety at intake were associated with receiving ADHD treatment.
, , , et al
JCP
Long-Term Safety and Treatment Effect of Olanzapine/Samidorphan
Original Research

December 4, 2024

During up to 4 years of treatment, the combination of olanzapine/samidorphan was safe and well-tolerated, and patients’ symptoms remained stable.
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Review Articles

JCP
Economic Impact of Cognitive Impairment and Negative Symptoms in Schizophrenia
Review Article

August 21, 2024

Patients with schizophrenia and cognitive impairment had a 100% increase in relapse-related hospitalizations and ER visits versus patients with no (or only mild) cognitive impairment.
, , , et al
JCP
Cognitive Effects of ECT in Schizophrenia: A Review
Review Article

June 5, 2024

ECT was not associated with any significant cognitive deficits in people with treatment-resistant schizophrenia across global cognition, attention, language, visuospatial function, and executive function domains. The majority of studies…
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JCP
Interpersonal Psychotherapy for PTSD: A Critical Review
Review Article

May 29, 2024

This critical review will give clinicians confidence in considering IPT as an alternative to exposure treatments for posttraumatic stress disorder.
JCP
Omega-3 PUFA Supplements for ADHD
Meta-Analysis

August 30, 2023

Although omega-3 polyunsaturated fatty acids (PUFAs) may not improve core symptoms of attention-deficit/hyperactivity disorder, longer-term PUFA supplementation may have potential benefits.
, , , et al
JCP
Mechanisms of Treatment of Bipolar Disorder and Borderline Personality Disorder: Brain Imaging Research
Meta-Analysis

March 27, 2023

Different brain regions were changed with psychotherapy versus medication. The findings may help with predicting treatment efficacy and identifying treatment biomarkers in these disorders.
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JCP
Antipsychotic Dose and Weight Gain
Meta-Analysis

February 8, 2023

Although effects on weight gain have been explored for several antipsychotics, the role of dose in producing these effects has not been widely studied. This meta-analysis examined the association…
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ASCP Corner

Letters to the Editor

JCP
Mental Health Assessment and Psychosocial Intervention in Maternal-Fetal Interventions
Letter to the Editor

November 18, 2024

In discussing a recent JCP letter to the editor, Akerson et al recommend that centers for fetal diagnosis and treatment include a social worker who can provide psychosocial assessment,…
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JCP
Clarification Regarding the Psychiatrist’s Role—Reply to Akerson et al
Letter to the Editor

November 18, 2024

The authors respond to a letter by Akerson et al.
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JCP
Detecting Misuse of Prescription Opioids
Letter to the Editor

October 21, 2024

The authors discuss the difficulty in screening for opioid misuse and the need for clinicians to gain confidence in initiating difficult discussions with patients on long-term opioid treatment.
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JCP
Mental Health Assessments for Fetal Interventions
Letter to the Editor

June 24, 2024

The authors offer guidance and raise awareness about the intersection of maternal mental health and fetal interventions.
JCP
Why Ask Patients to Cut Into Quarters 10 mg THC Gummies From a Dispensary When 2.5 mg THC Is Available by Prescription?
Letter to the Editor

June 5, 2024

The authors discuss a study by Sawicki et al of dementia patients for whom 2.5 mg of THC was recommended for neuropsychiatric symptoms.
,
JCP
THC Edible Gummies for Behavioral Symptoms of Dementia: Reply to Goldman and Markov
Letter to the Editor

June 5, 2024

The authors reply to Goldman and Markov’s comments on their recent study of dispensary-obtained THC for dementia.
,

Commentaries

JCP
Evolving Care and Research Priorities in ADHD
Commentary

December 23, 2024

Surman and Wilens discuss two recent JCP articles highlighting that how ADHD manifests can be heavily influenced by context, as well as individual vulnerabilities and strengths.
,
JCP
The Opioid Industry's Legacy: A Generation of Prescribed Suffering
Commentary

December 18, 2024

The authors discuss the influential and far-reaching effects of messaging from the opioid industry on the opioid use epidemic.
,
JCP
SUD Programs for Transgender and Gender Diverse Patients
Commentary

November 11, 2024

The authors discuss responsiveness of transgender and gender diverse patients to SUD treatment at different care levels (eg, outpatient, residential, inpatient), as well as how to reduce stressors and…
,
JCP
Clinical Implications of Adult ADHD: What New Data Tell Us
Commentary

October 10, 2024

The authors discuss striking new findings from the Morbidity and Mortality Weekly Report on the burden of adult ADHD, demonstrating the need for the upcoming APSARD Adult ADHD Guidelines.
,
JCP
Reproductive Pharmacovigilance and Best Practices
Commentary

August 26, 2024

Dr Freeman discusses a recent study by Pacilio et al that characterized real world practices around ketamine treatment and pregnancy testing, consent processes, and contraception use. She emphasizes the…
JCP
Functional Unblinding in Pivotal Studies and the Future of Psychedelic Medicine
Commentary

August 21, 2024

Dr Rosenbaum comments on the challenge of evaluating trials of treatments whose effects are unmistakable, and how this dilemma may be addressed.

More JCP Articles

JCP
Efficacy and Safety of Memantine for Children and Adults with ADHD
Systematic Review

December 25, 2024

Although most studies involved small patient groups, memantine showed potential benefits in managing ADHD symptoms and had a favorable safety profile.
, , , et al
JCP
Cannabis Use in Pregnancy and ASD or ADHD in Offspring
Clinical and Practical Psychopharmacology

December 23, 2024

Although the number of cannabis-exposed pregnancies (with ASD and ADHD as the outcomes) in world literature is small, cannabis use during pregnancy is a clear marker for adverse neurodevelopmental…
JCP
Sex Differences in PTSD among US Military Veterans
Brief Report

December 16, 2024

Sex differences in PTSD were attributable to differential exposure to traumatic events such as childhood sexual assault and military sexual trauma and to social factors such as greater loneliness.
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JCP
Sex Differences in Antidepressant Acceptability
Original Research

December 4, 2024

This study provides evidence of sex differences in antidepressant acceptability, with fluoxetine more acceptable for men than women and the reverse true for paroxetine. Findings suggest the importance of…
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JCP
Difficult to Treat Depression: Focus on Approach, Algorithms, and Access
Academic Highlights

November 25, 2024

The Southwest Forum on Difficult to Treat Depression brought together 11 experts to discuss aspects of managing difficult-to-treat depression. This article presents highlights from the forum, covering such topics…
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JCP
PTSD and Risk of Suicide Reattempt
Original Research

November 25, 2024

After controlling for comorbid psychiatric conditions and other variables, PTSD was associated with suicide reattempt at 6 months (OR= 2.33) and with rehospitalization in psychiatric settings (OR=2.24) and nonpsychiatric…
, , , et al
JCP
Understanding Meta-Analysis Using Gestational Exposure to Cannabis and Birth Defects
Clinical and Practical Psychopharmacology

November 20, 2024

Dr Andrade discusses strengths and limitations of two recent meta-analyses on birth defects associated with cannabis exposure, with a view to providing readers with a deeper understanding of how…
JCP
MDD and Bipolar Disorder in Black and White Postpartum Women
Original Research

November 20, 2024

No significant difference was observed in the rate of postpartum MDD in Black (40%) versus white (35%) women. However, bipolar disorder significantly differed between Black (19.2%) and white (11.5%)…
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JCP
What Is the Role of the Muscarinic Receptor System in Schizophrenia?
Insights

November 19, 2024

In this video, Dr. Correll discusses the role of the muscarinic receptor system in schizophrenia, exploring its impact on cognitive and functional outcomes. He examines the potential for _targeting…
JCP
What are the Efficacy and Safety of Muscarinic Receptor Modulators in Patients With Schizophrenia?
Insights

November 19, 2024

In this video, Dr. Correll examines the therapeutic potential of the muscarinic receptor system in schizophrenia treatment. He discusses how _targeting muscarinic receptors may address cognitive and functional impairments,…
JCP
What is the Place of Muscarinic Receptor Modulators in the Clinical Care of Patients With Schizophrenia?
Insights

November 19, 2024

This video features Dr. Christoph Correll discussing the clinical application of muscarinic receptor modulators in schizophrenia treatment. He explores their unique mechanism of action, compares them to traditional antipsychotics,…
JCP
Hyperbaric Oxygen Therapy for Combat-Associated PTSD
Original Research

November 10, 2024

Hyperbaric oxygen therapy demonstrated significant improvements on measures of depression in male veterans with combat-associated PTSD.
, , , et al

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