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Eteplirsen for the Treatment of Duchenne Muscular Dystrophy: Quality of Evidence Concerns—an Alternative Viewpoint

Several novel therapies to increase production of dystrophin in myocytes are discussed, of which, eteplirsen (Exondys) is the only currently approved by the US Food & Drug Administration (FDA).
Wiley (opens in a new tab)

Pharmacist's role in an interdisciplinary cardiac rehabilitation team.

Pharmacists can play a vital role as part of an interdisciplinary cardiac rehabilitation team to ensure proper adherence to cardiac medications and patient safety through patient education and interventions.
PubMed (opens in a new tab)

Medication Induced Changes in Lipid and Lipoproteins

Effect of relaxing hepatitis C treatment restrictions on direct-acting antiviral use in a Medicaid program: an interrupted time series analysis

Reducing coverage limitations resulted in treatment of patients with fewer liver-related complications and more substance use disorders, and additional interventions may be necessary to meet HCV elimination goals.
PDF (opens in a new tab)

The safety and efficacy of vortioxetine for acute treatment of major depressive disorder: a systematic review and meta-analysis

Vortioxetine was significantly more effective than placebo for acute treatment of major depressive disorder (MDD).
Springer (opens in a new tab)

Polypharmacy in Multiple Sclerosis: Prevalence, Risks, and Mitigation Strategies

People with multiple sclerosis are at risk for inappropriate polypharmacy, and multiple sclerosis providers should focus on the appropriateness and risks versus benefits of pharmacotherapy in each patient.
Springer (opens in a new tab)

Frequency and clinical outcomes of pharmacist-driven switching from warfarin to direct oral anticoagulants in an underserved patient population: A retrospective cohort study.

No increase in harm was observed 6 months after switch assessment when pharmacists at a family medicine clinic switched underserved patients from warfarin to DOACs, and laboratory monitoring after switches was consistent with current recommendations.
PubMed (opens in a new tab)

Current Use of Statins for Primary Prevention of Cardiovascular Disease: Patient-Reported Outcomes and Adherence

Clinicians must engage patients in a shared decision about starting new statin therapy, which should involve discussion about the risks and benefits of therapy, patient perceptions, and health status.
Springer (opens in a new tab)

A randomized controlled trial for a peer-facilitated telemedicine hepatitis c treatment intervention for people who use drugs in rural communities: study protocol for the “peer tele-HCV” study

It is hypothesize that the peer tele-HCV model will increase treatment initiation, treatment completion, SVR12 rates, and engagement with harm reduction services compared to EUC.
Springer (opens in a new tab)

Polypharmacy in multiple sclerosis: More is not necessarily better

Despite disease-modifying therapies controlling multiple sclerosis, MS causes a range of symptoms that impact quality of life and neurologists often respond by prescribing medications, which can cause health problems.
SAGE (opens in a new tab)
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