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ESC Guidelines on the Management of Cardiovascular Diseases During Pregnancy

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2021 ESC Guidelines on cardiovascular disease prevention in clinical practice.

PubMed (opens in a new tab)

ESC Guidelines on the management of cardiovascular diseases during pregnancy

Authors/Task Force Members Vera Regitz-Zagrosek (Chairperson) (Germany)*, Carina Blomstrom Lundqvist (Sweden), Claudio Borghi (Italy), Renata Cifkova (Czech Republic), Rafael Ferreira (Portugal),…

Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology…

The present position statement offers a state‐of‐the‐art summary of what is known about risk factors for potential pathophysiological mechanisms, clinical presentation of, and diagnosis and management of PPCM.
Wiley (opens in a new tab)

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

A loss-of-function mutation in the gene encoding RNA binding motif protein 20 (Rbm20) is identified as the underlying cause of pathological titin isoform expression and a set of 30 genes with conserved splicing regulation between humans and rats is identified.
Nature (opens in a new tab)

Impact of sex and gender on COVID-19 outcomes in Europe

Clinical and epidemiological evidence for gender and sex differences in COVID-19 from Europe and China is summarized and the need to better understand the impact of sex and gender on incidence and case fatality of the disease is emphasized.
Springer (opens in a new tab)

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy.

PubMed (opens in a new tab)

Gender differences in the metabolic syndrome and their role for cardiovascular disease

The presently available data suggest that the pathophysiology of the metabolic syndrome and its contribution to the relative risk of cardiovascular events and heart failure show gender differences, which might be of potential relevance for prevention, diagnostics, and therapy of the syndrome.
Springer (opens in a new tab)

Mechanistic Pathways of Sex Differences in Cardiovascular Disease.

There is a need for a more detailed understanding of sex differences and their underlying mechanisms, which holds the potential to design new drugs that _target sex-specific cardiovascular mechanisms and affect phenotypes.
PubMed (opens in a new tab)

Contribution of comorbidities to functional impairment is higher in heart failure with preserved than with reduced ejection fraction

The impact of comorbidities on physical impairment is higher in HFpEF than in HFrEF, and also much stronger than the impact of a 10% decrease in ejection fraction in H FrEF or a 5 mm decrease in left ventricular end-diastolic diameter inHFpEF.
Springer (opens in a new tab)
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